It is used for treatment of ulcer defects mucous a stomach and a duodenum, in a combination with a suitable antibiotic allows to achieve the best effect of an eradikation of Helicobacter pylori (90% of cases). As a rule, at complex treatment of stomach ulcer after the end of reception of antibiotics there is no need for continuation of antisekretorny monotherapy.
Clinical trials showed that at preparation reception the contents gastrin in blood increases in response to reduction of production of hydrochloric acid. Increase of number of endocrine cages which develop a histamine, happens at the expense of increase in concentration gastrin in blood. The increase in frequency of emergence of granular cysts mucous a stomach was in certain cases observed at long use the antisekretornykh of preparations. This phenomenon is regarded as physiologic in response to oppression of production of hydrochloric acid. Cysts always are good-quality and tranzitorny (after the termination of a course of treatment disappear).
Omeprazol is effective for prevention of formation of peptic ulcers at accompanying therapy by nonsteroid resolvents (even inhibitors cyclooxygenase - 2 selective groups).
The drug takes effect within 60 minutes after taking 20-40 mg of esomeprazole. Repeated application of 20 mg of esomeprazole within 24 hours once a day one followed by a reduction of gastric secretions due to the effect of pentagastrin by 90% for approximately 5 days administration.Continue reading...